Resveratrol is a type of polyphenol. There are two
types in nature, cis- and trans-. The trans-resveratrol, rather than cis-streoisomer is the active form we have used which comes from Japanese knotweed (Polygonum cuspidatim).
Resveratrol is typically associated with red grapes.
However knotweed has the richest, most available
source of resveratrol.
Resveratrol’s effects against aging may be similar
to the effects of calorie restriction and be due to
the increase expression of the enzyme sirtuin.ii These
are NAD+ dependant enzymes, used in the
prevention of age-related disorders.
Resveratrol assists with the prevention of
neuro-degenerative disorders. It stabilises levels of
beta-amyloid peptide, ultimately reducing
oxidative stress and neuro-inflammation. These
properties enable a good level of support against
Resveratrol is an antioxidant that has the ability to
protect against damage to DNA and the
mitochondria. It has been studied for its
anti-mutigenic and anti-tumour and its metastasis
It is thought that resveratrol is even stronger than
NSAIDs as an anti-inflammatory, and has none of
the side effects. It does this by inhibition of
interleukin 8, NFkB and COX.
Resveratrol has been found to increase insulin
sensitivity and decrease IGF-1. Therefore
resveratrol is a useful tool in the treatment of
The utilisation of both resveratrol and quercetin has
shown tremendous benefits including support
against certain tumors.vii One study showed that, on
their own, they didn’t have an effect on weight.
Together however, they significantly reduced
adipose tissue weight.
EGCG (epigallocatechin-gallate) is a constituent of
green tea which has been found to have