Quick Summary

Maqui Berry (Aristotelia chilensis) is a berry native to Chile, recognized for its high content of anthocyanins and other polyphenols with antioxidant properties. It is currently under research for potential health applications including antioxidant, anti-inflammatory, and possible kidney-protective effects. Most evidence comes from preclinical studies, with limited but emerging human clinical data. Further clinical trials are needed to better understand its efficacy and safety.

What Is It

Maqui Berry is a dark purple fruit harvested primarily in Chile and known for its rich polyphenol composition, especially anthocyanins, which contribute to its vibrant color and biological activities. It has traditionally been consumed as a food and used in local folk remedies.

Traditional Uses

Traditionally, Maqui Berry has been used in South American indigenous cultures for its purported general health benefits, including anti-inflammatory and antioxidant effects. It has been consumed fresh or in juices and preserves.

Active Compounds

  • Anthocyanins – pigments with antioxidant activity
  • Polyphenols – including flavonoids and phenolic acids

Potential Benefits with Evidence Levels

  • Antioxidant Activity – Moderate preclinical and limited human evidence suggests Maqui’s anthocyanins provide antioxidant effects (Tiscornia et al., 2026; Stote et al., 2023; Sadowska-Bartosz & Bartosz, 2024). Some human studies indicate reduced oxidative stress markers, though results are mixed.
  • Anti-Inflammatory Properties – Mainly supported by preclinical and mechanistic reviews, Maqui’s bioactive compounds may contribute to reducing inflammation (Ramírez-Torres et al., 2025; 2023 systematic reviews). Direct clinical evidence in humans is limited.
  • Potential Nephroprotective Effects – Preclinical studies suggest antioxidant and anti-inflammatory benefits that could protect kidney function in chronic kidney disease models (Tiscornia et al., 2025). Human data are sparse and inconclusive.
  • Metabolic Health and Glycemic Regulation – Limited preclinical and observational data indicate polyphenols in berries including Maqui may support improved glycemic control and metabolic health (Governa et al., 2018; Hameed et al., 2020). Specific clinical efficacy for Maqui remains to be firmly established.

Side Effects

No specific adverse effects associated with Maqui Berry consumption have been reported in available studies. However, the current evidence is insufficient to rule out rare or long-term effects.

Drug Interactions

There is no documented evidence from human studies of drug interactions with Maqui Berry. Due to its polyphenol content, theoretical interactions with drugs metabolized by oxidative pathways may exist but remain unconfirmed.

Who Should Avoid It

No specific contraindications for Maqui Berry have been established. Caution is recommended for individuals with chronic health conditions or those taking medications until more research is available.

Pregnancy and Breastfeeding Caution

Insufficient evidence exists regarding the safety of Maqui Berry during pregnancy and breastfeeding. Use during these periods should be approached cautiously and under medical supervision.

Evidence Limitations

  • Most studies are preclinical (in vitro or animal models) with limited, small-scale human trials.
  • Human trials often lack control groups and tend to be short-term.
  • Low bioavailability of Maqui anthocyanins may complicate translation of benefits observed in laboratory models to humans.
  • No standardized dosing or preparation has been established for therapeutic use.
  • Data on interactions with drugs or chronic disease conditions are lacking.
  • No large randomized controlled trials have conclusively evaluated clinical benefits or risks.

References

Last Reviewed

June 2024

Disclaimer: This page is for informational purposes only and does not constitute medical advice. Consult a healthcare professional before using Maqui Berry, especially if you are pregnant, breastfeeding, have a medical condition, or are taking medications.